Blockade of TNF-α signaling benefits cancer therapy by suppressing effector regulatory T cell expansion

Effector but not naive regulatory T cells (Treg cells) can accumulate in the peripheral blood as well as the tumor microenvironment, expand during tumor progression and be one of the main suppressors for antitumor immunity. However, the underlying mechanisms for effector Treg cell expansion in tumor...

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Dettagli Bibliografici
Pubblicato in:Oncoimmunology
Autori principali: Chang, Li-Yuan, Lin, Yung-Chang, Chiang, Jy-Ming, Mahalingam, Jayashri, Su, Shih-Huan, Huang, Ching-Tai, Chen, Wei-Ting, Huang, Chien-Hao, Jeng, Wen-Juei, Chen, Yi-Cheng, Lin, Shi-Ming, Sheen, I-Shyan, Lin, Chun-Yen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2015
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589045/
https://ncbi.nlm.nih.gov/pubmed/26451304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1040215
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