Blockade of TNF-α signaling benefits cancer therapy by suppressing effector regulatory T cell expansion

Effector but not naive regulatory T cells (Treg cells) can accumulate in the peripheral blood as well as the tumor microenvironment, expand during tumor progression and be one of the main suppressors for antitumor immunity. However, the underlying mechanisms for effector Treg cell expansion in tumor...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Chang, Li-Yuan, Lin, Yung-Chang, Chiang, Jy-Ming, Mahalingam, Jayashri, Su, Shih-Huan, Huang, Ching-Tai, Chen, Wei-Ting, Huang, Chien-Hao, Jeng, Wen-Juei, Chen, Yi-Cheng, Lin, Shi-Ming, Sheen, I-Shyan, Lin, Chun-Yen
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589045/
https://ncbi.nlm.nih.gov/pubmed/26451304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1040215
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