CD4(+) T Cells Expressing Latency-Associated Peptide and Foxp3 Are an Activated Subgroup of Regulatory T Cells Enriched in Patients with Colorectal Cancer

Latency-associated peptide (LAP) - expressing regulatory T cells (Tregs) are important for immunological self-tolerance and immune homeostasis. In order to investigate the role of LAP in human CD4(+)Foxp3(+) Tregs, we designed a cross-sectional study that involved 42 colorectal cancer (CRC) patients...

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Detalhes bibliográficos
Main Authors: Mahalingam, Jayashri, Lin, Chun-Yen, Chiang, Jy-Ming, Su, Po-Jung, Chu, Yu-Yi, Lai, Hsin-Yi, Fang, Jian-He, Huang, Ching-Tai, Lin, Yung-Chang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182495/
https://ncbi.nlm.nih.gov/pubmed/25268580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108554
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