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Analysis by a highly sensitive split luciferase assay of the regions involved in APP dimerization and its impact on processing
Alzheimer’s disease (AD) is a neurodegenerative disease that causes progressive loss of cognitive functions, leading to dementia. Two types of lesions are found in AD brains: neurofibrillary tangles and senile plaques. The latter are composed mainly of the β-amyloid peptide (Aβ) generated by amyloid...
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| Опубликовано в: : | FEBS Open Bio |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4588712/ https://ncbi.nlm.nih.gov/pubmed/26500837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2015.09.002 |
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