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AAV9 supports wide-scale transduction of the CNS and TDP-43 disease modeling in adult rats
AAV9 has emerged as an efficient adeno-associated virus (AAV) serotype for gene transfer to the central nervous system. We have used this technique to study aspects of amyotrophic lateral sclerosis (ALS) by administering AAV encoding the ALS-related gene transactive response DNA binding protein of 4...
Enregistré dans:
| Publié dans: | Mol Ther Methods Clin Dev |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4588447/ https://ncbi.nlm.nih.gov/pubmed/26445725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2015.36 |
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