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Highly Effective Non-Viral Antitumor Gene Therapy System Comprised of Biocompatible Small Plasmid Complex Particles Consisting of pDNA, Anionic Polysaccharide, and Fully Deprotected Linear Polyethylenimine

We have reported that ternary complexes of plasmid DNA with conventional linear polyethylenimine (l-PEI) and certain polyanions were very stably dispersed, and, with no cryoprotectant, they could be freeze-dried and re-hydrated without the loss of transfection ability. These properties enabled the p...

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Dettagli Bibliografici
Pubblicato in:Pharmaceutics
Autori principali: Koyama, Yoshiyuki, Sugiura, Kikuya, Yoshihara, Chieko, Inaba, Toshio, Ito, Tomoko
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588191/
https://ncbi.nlm.nih.gov/pubmed/26213961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics7030152
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