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Novel Antitumor Strategy Utilizing a Plasmid Expressing a Mycobacterium tuberculosis Antigen as a “Danger Signal” to Block Immune Escape of Tumor Cells

Immune escape of tumor cells is one of the main obstacles hindering the effectiveness of cancer immunotherapy. We developed a novel strategy to block immune escape by transfecting tumor cells in vivo with genes of pathogenic antigens from Mycobacterium tuberculosis (TB). This induces presentation of...

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Bibliografiske detaljer
Udgivet i:Pharmaceutics
Main Authors: Koyama, Yoshiyuki, Yoshihara, Chieko, Ito, Tomoko
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588192/
https://ncbi.nlm.nih.gov/pubmed/26213962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics7030165
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