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Highly Effective Non-Viral Antitumor Gene Therapy System Comprised of Biocompatible Small Plasmid Complex Particles Consisting of pDNA, Anionic Polysaccharide, and Fully Deprotected Linear Polyethylenimine

We have reported that ternary complexes of plasmid DNA with conventional linear polyethylenimine (l-PEI) and certain polyanions were very stably dispersed, and, with no cryoprotectant, they could be freeze-dried and re-hydrated without the loss of transfection ability. These properties enabled the p...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Koyama, Yoshiyuki, Sugiura, Kikuya, Yoshihara, Chieko, Inaba, Toshio, Ito, Tomoko
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588191/
https://ncbi.nlm.nih.gov/pubmed/26213961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics7030152
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