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Loosening of DNA/Polycation Complexes by Synthetic Polyampholyte to Improve the Transcription Efficiency: Effect of Charge Balance in the Polyampholyte
High mobililty group proteins are amphoteric nuclear proteins that are known to unfold chromatin to stimulate transcription. To mimic their structures, we synthesized the novel polyethylene glycol (PEG) derivatives, PEG-ACs, consisting of both amino- and carboxyl-pendants in various ratios, and thei...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2849077/ https://ncbi.nlm.nih.gov/pubmed/20371325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.11.047 |
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