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Structural Basis of Targeting the Exportin CRM1 in Cancer

Recent studies have demonstrated the interference of nucleocytoplasmic trafficking with the establishment and maintenance of various cancers. Nucleocytoplasmic transport is highly regulated and coordinated, involving different nuclear transport factors or receptors, importins and exportins, that med...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Dickmanns, Achim, Monecke, Thomas, Ficner, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588050/
https://ncbi.nlm.nih.gov/pubmed/26402707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells4030538
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