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Transgelin gene is frequently downregulated by promoter DNA hypermethylation in breast cancer

BACKGROUND: CpG hypermethylation in gene promoters is a frequent mechanism of tumor suppressor gene silencing in various types of cancers. It usually occurs at early steps of cancer progression and can be detected easily, giving rise to development of promising biomarkers for both detection and prog...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Clin Epigenetics
मुख्य लेखकों: Sayar, Nilufer, Karahan, Gurbet, Konu, Ozlen, Bozkurt, Betul, Bozdogan, Onder, Yulug, Isik G.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587865/
https://ncbi.nlm.nih.gov/pubmed/26421063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0138-5
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