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SIP1 is downregulated in hepatocellular carcinoma by promoter hypermethylation

BACKGROUND: Smad interacting protein-1 is a transcription factor that is implicated in transforming growth factor-β/bone morphogenetic protein signaling and a repressor of E-cadherin and human telomerase reverse transcriptase. It is also involved in epithelial-mesenchymal transition and tumorigenesi...

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Hlavní autoři: Acun, Tolga, Oztas, Emin, Yagci, Tamer, Yakicier, Mustafa C
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118200/
https://ncbi.nlm.nih.gov/pubmed/21645397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-223
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