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Transgelin gene is frequently downregulated by promoter DNA hypermethylation in breast cancer

BACKGROUND: CpG hypermethylation in gene promoters is a frequent mechanism of tumor suppressor gene silencing in various types of cancers. It usually occurs at early steps of cancer progression and can be detected easily, giving rise to development of promising biomarkers for both detection and prog...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Sayar, Nilufer, Karahan, Gurbet, Konu, Ozlen, Bozkurt, Betul, Bozdogan, Onder, Yulug, Isik G.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587865/
https://ncbi.nlm.nih.gov/pubmed/26421063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0138-5
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