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Transgelin gene is frequently downregulated by promoter DNA hypermethylation in breast cancer

BACKGROUND: CpG hypermethylation in gene promoters is a frequent mechanism of tumor suppressor gene silencing in various types of cancers. It usually occurs at early steps of cancer progression and can be detected easily, giving rise to development of promising biomarkers for both detection and prog...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Clin Epigenetics
Päätekijät: Sayar, Nilufer, Karahan, Gurbet, Konu, Ozlen, Bozkurt, Betul, Bozdogan, Onder, Yulug, Isik G.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587865/
https://ncbi.nlm.nih.gov/pubmed/26421063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0138-5
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