Visualization of Active Glucocerebrosidase in Rodent Brain with High Spatial Resolution following In Situ Labeling with Fluorescent Activity Based Probes

Gaucher disease is characterized by lysosomal accumulation of glucosylceramide due to deficient activity of lysosomal glucocerebrosidase (GBA). In cells, glucosylceramide is also degraded outside lysosomes by the enzyme glucosylceramidase 2 (GBA2) of which inherited deficiency is associated with ata...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:PLoS One
Κύριοι συγγραφείς: Herrera Moro Chao, Daniela, Kallemeijn, Wouter W., Marques, Andre R. A., Orre, Marie, Ottenhoff, Roelof, van Roomen, Cindy, Foppen, Ewout, Renner, Maria C., Moeton, Martina, van Eijk, Marco, Boot, Rolf G., Kamphuis, Willem, Hol, Elly M., Aten, Jan, Overkleeft, Hermen S., Kalsbeek, Andries, Aerts, Johannes M. F. G.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2015
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587854/
https://ncbi.nlm.nih.gov/pubmed/26418157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138107
Ετικέτες: Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!

Παρόμοια τεκμήρια