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Reduction in SGLT1 mRNA Expression in the Ventromedial Hypothalamus Improves the Counterregulatory Responses to Hypoglycemia in Recurrently Hypoglycemic and Diabetic Rats

The objective of this study was to determine whether the sodium-glucose transporter SGLT1 in the ventromedial hypothalamus (VMH) plays a role in glucose sensing and in regulating the counterregulatory response to hypoglycemia, and if so, whether knockdown of in the VMH can improve counterregulatory...

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Библиографические подробности
Опубликовано в: :Diabetes
Главные авторы: Fan, Xiaoning, Chan, Owen, Ding, Yuyan, Zhu, Wanling, Mastaitis, Jason, Sherwin, Robert
Формат: Artigo
Язык:Inglês
Опубликовано: American Diabetes Association 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587643/
https://ncbi.nlm.nih.gov/pubmed/26130763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-0022
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