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Increased GABAergic Tone in the Ventromedial Hypothalamus Contributes to Suppression of Counterregulatory Reponses After Antecedent Hypoglycemia

OBJECTIVE: We have previously demonstrated that modulation of γ-aminobutyric acid (GABA) inhibitory tone in the ventromedial hypothalamus (VMH), an important glucose-sensing region in the brain, modulates the magnitude of glucagon and sympathoadrenal responses to hypoglycemia. In the current study,...

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Bibliografiske detaljer
Udgivet i:Diabetes
Main Authors: Chan, Owen, Cheng, Haiying, Herzog, Raimund, Czyzyk, Daniel, Zhu, Wanling, Wang, Ajin, McCrimmon, Rory J., Seashore, Margretta R., Sherwin, Robert S.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518793/
https://ncbi.nlm.nih.gov/pubmed/18375441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db07-1559
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