Lactate-Induced Release of GABA in the Ventromedial Hypothalamus Contributes to Counterregulatory Failure in Recurrent Hypoglycemia and Diabetes

Suppression of GABAergic neurotransmission in the ventromedial hypothalamus (VMH) is crucial for full activation of counterregulatory responses to hypoglycemia, and increased γ-aminobutyric acid (GABA) output contributes to counterregulatory failure in recurrently hypoglycemic (RH) and diabetic rats...

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Detalhes bibliográficos
Main Authors: Chan, Owen, Paranjape, Sachin A., Horblitt, Adam, Zhu, Wanling, Sherwin, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837027/
https://ncbi.nlm.nih.gov/pubmed/23939392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0770
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