Lactate-Induced Release of GABA in the Ventromedial Hypothalamus Contributes to Counterregulatory Failure in Recurrent Hypoglycemia and Diabetes

Suppression of GABAergic neurotransmission in the ventromedial hypothalamus (VMH) is crucial for full activation of counterregulatory responses to hypoglycemia, and increased γ-aminobutyric acid (GABA) output contributes to counterregulatory failure in recurrently hypoglycemic (RH) and diabetic rats...

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Bibliographic Details
Main Authors: Chan, Owen, Paranjape, Sachin A., Horblitt, Adam, Zhu, Wanling, Sherwin, Robert S.
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2013
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837027/
https://ncbi.nlm.nih.gov/pubmed/23939392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0770
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