Reduction in SGLT1 mRNA Expression in the Ventromedial Hypothalamus Improves the Counterregulatory Responses to Hypoglycemia in Recurrently Hypoglycemic and Diabetic Rats

The objective of this study was to determine whether the sodium-glucose transporter SGLT1 in the ventromedial hypothalamus (VMH) plays a role in glucose sensing and in regulating the counterregulatory response to hypoglycemia, and if so, whether knockdown of in the VMH can improve counterregulatory...

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Bibliographic Details
Published in:Diabetes
Main Authors: Fan, Xiaoning, Chan, Owen, Ding, Yuyan, Zhu, Wanling, Mastaitis, Jason, Sherwin, Robert
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2015
Subjects:
Complications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587643/
https://ncbi.nlm.nih.gov/pubmed/26130763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-0022
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