Mesoporous Silica Nanoparticle Delivery of Chemically Modified siRNA Against TWIST1 Leads to Reduced Tumor Burden

Growth and progression of solid tumors depends on the integration of multiple pro-growth and survival signals, including the induction of angiogenesis. TWIST1 is a transcription factor whose reactivation in tumors leads to epithelial to mesenchymal transition (EMT), including increased cancer cell s...

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發表在:Nanomedicine
Main Authors: Finlay, James, Roberts, Cai M., Dong, Juyao, Zink, Jeffrey I., Tamanoi, Fuyuhiko, Glackin, Carlotta A.
格式: Artigo
語言:Inglês
出版: 2015
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587301/
https://ncbi.nlm.nih.gov/pubmed/26115637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2015.05.011
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