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Enhanced Gene and siRNA Delivery by Polycation-Modified Mesoporous Silica Nanoparticles Loaded with Chloroquine

PURPOSE: To prepare mesoporous silica-based delivery systems capable of simultaneous delivery of drugs and nucleic acids. METHODS: The surface of mesoporous silica nanoparticles (MSN) was modified with poly(ethylene glycol) (PEG) and poly(2-(dimethylamino)ethylmethacrylate) (PDMAEMA) or poly (2-(die...

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Detalhes bibliográficos
Main Authors: Bhattarai, Shanta Raj, Muthuswamy, Elayaraja, Wani, Amit, Brichacek, Michal, Castañeda, Antonio L., Brock, Stephanie L., Oupicky, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4108588/
https://ncbi.nlm.nih.gov/pubmed/20730557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-010-0245-0
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