Mesoporous Silica Nanoparticle Delivery of Chemically Modified siRNA Against TWIST1 Leads to Reduced Tumor Burden

Growth and progression of solid tumors depends on the integration of multiple pro-growth and survival signals, including the induction of angiogenesis. TWIST1 is a transcription factor whose reactivation in tumors leads to epithelial to mesenchymal transition (EMT), including increased cancer cell s...

Full description

Saved in:

Bibliographic Details
Published in:	Nanomedicine
Main Authors:	Finlay, James, Roberts, Cai M., Dong, Juyao, Zink, Jeffrey I., Tamanoi, Fuyuhiko, Glackin, Carlotta A.
Format:	Artigo
Language:	Inglês
Published:	2015
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4587301/ https://ncbi.nlm.nih.gov/pubmed/26115637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2015.05.011
Tags:	Add Tag No Tags, Be the first to tag this record!

Mesoporous Silica Nanoparticle Delivery of Chemically Modified siRNA Against TWIST1 Leads to Reduced Tumor Burden

Similar Items