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Optimizing the design of protein nanoparticles as carriers for vaccine applications

Successful vaccine development remains a huge challenge for infectious diseases such as malaria, HIV and influenza. As a novel way to present antigenic epitopes to the immune system, we have developed icosahedral self-assembling protein nanoparticles (SAPNs) to serve as a prototypical vaccine platfo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nanomedicine
Hauptverfasser: Doll, Tais A.P.F., Neef, Tobias, Duong, Nha, Lanar, David E., Ringler, Philippe, Müller, Shirley A., Burkhard, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier Inc. 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587294/
https://ncbi.nlm.nih.gov/pubmed/26051652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2015.05.003
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