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Optimizing the refolding conditions of self-assembling polypeptide nanoparticles that serve as repetitive antigen display systems

Nanoparticles show great promise as potent vaccine candidates since they are readily taken up by the antigen presenting cells of the immune system. The particle size and the density of the B cell epitopes on the surface of the particles greatly influences the strength of the humoral immune response....

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Pubblicato in:J Struct Biol
Autori principali: Yang, Yongkun, Ringler, Philippe, Müller, Shirley A., Burkhard, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier Inc. 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7118850/
https://ncbi.nlm.nih.gov/pubmed/22115997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2011.11.011
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