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Ubiquitin plays an atypical role in GPCR-induced p38 MAP kinase activation on endosomes
Protease-activated receptor 1 (PAR1) is a G protein–coupled receptor (GPCR) for thrombin and promotes inflammatory responses through multiple pathways including p38 mitogen-activated protein kinase signaling. The mechanisms that govern PAR1-induced p38 activation remain unclear. Here, we define an a...
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Опубликовано в: : | J Cell Biol |
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Главные авторы: | , , , , , , , |
Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
The Rockefeller University Press
2015
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4586747/ https://ncbi.nlm.nih.gov/pubmed/26391660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201504007 |
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