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Atypical regulation of G protein-coupled receptor intracellular trafficking by ubiquitination
G protein-coupled receptor (GPCR) signaling is precisely regulated. After activation, GPCRs are desensitized, internalized and either recycled to the cell surface or sorted to lysosomes for degradation. The main route for GPCR lysosomal sorting requires ubiquitination and the endosomal-sorting compl...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4020713/ https://ncbi.nlm.nih.gov/pubmed/24680429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2013.11.004 |
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