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Downregulating p22phox ameliorates inflammatory response in Angiotensin II-induced oxidative stress by regulating MAPK and NF-κB pathways in ARPE-19 cells

Oxidative stress and inflammation are two interrelated biological events implicated in the pathogenesis of many diseases. Reactive oxygen species (ROS) produced under oxidative stress play a key role in pathological conditions. Inhibition of p22phox, an indispensable component of the NADPH oxidase (...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Qiu, Yiguo, Tao, Lifei, Lei, Chunyan, Wang, Jiaming, Yang, Peizeng, Li, Qiuhong, Lei, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586461/
https://ncbi.nlm.nih.gov/pubmed/26415877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14362
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