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Transient mitochondrial permeability transition mediates excitotoxicity in glutamate-sensitive NSC34(D) motor neuron-like cells
Excitotoxicity plays a critical role in neurodegenerative disease. Cytosolic calcium overload and mitochondrial dysfunction are among the major mediators of high level glutamate-induced neuron death. Here, we show that the transient opening of mitochondrial permeability transition pore (tMPT) bridge...
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| Publicado no: | Exp Neurol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4586369/ https://ncbi.nlm.nih.gov/pubmed/26024861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2015.05.010 |
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