NSC-34 Motor Neuron-Like Cells Are Unsuitable as Experimental Model for Glutamate-Mediated Excitotoxicity

Glutamate-induced excitotoxicity is a major contributor to motor neuron degeneration in the pathogenesis of amyotrophic lateral sclerosis (ALS). The spinal cord × Neuroblastoma hybrid cell line (NSC-34) is often used as a bona fide cellular model to investigate the physiopathological mechanisms of A...

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Dades bibliogràfiques
Publicat a:Front Cell Neurosci
Autors principals: Madji Hounoum, Blandine, Vourc’h, Patrick, Felix, Romain, Corcia, Philippe, Patin, Franck, Guéguinou, Maxime, Potier-Cartereau, Marie, Vandier, Christophe, Raoul, Cédric, Andres, Christian R., Mavel, Sylvie, Blasco, Hélène
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2016
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860417/
https://ncbi.nlm.nih.gov/pubmed/27242431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00118
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