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NSC‐34 motor neuron‐like cells are sensitized to ferroptosis upon differentiation

Ferroptosis is a form of regulated cell death that is driven by lethal accumulation of lipid peroxides upon inhibition of glutathione peroxidase 4 (GPx4). Deletion of the Gpx4 gene in mice revealed that neurons are sensitive to ferroptosis in vivo. However, few studies have been conducted on ferropt...

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Bibliografiske detaljer
Udgivet i:FEBS Open Bio
Main Authors: Martinez, Alejandra M., Mirkovic, Jovan, Stanisz, Zofia A., Patwari, Fahmida S., Yang, Wan Seok
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443867/
https://ncbi.nlm.nih.gov/pubmed/30984534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12577
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