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Intrinsic ssDNA Annealing Activity in the C-Terminal Region of WRN()

Werner syndrome (WS) is a rare autosomal recessive disorder in humans characterized by premature aging and genetic instability. WS is caused by mutations in the WRN gene, which encodes a member of the RecQ family of DNA helicases. Cellular and biochemical studies suggest that WRN plays roles in DNA...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Muftuoglu, Meltem, Kulikowicz, Tomasz, Beck, Gad, Lee, Jae Wan, Piotrowski, Jason, Bohr, Vilhelm A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586260/
https://ncbi.nlm.nih.gov/pubmed/18771289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800807n
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