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Intrinsic ssDNA Annealing Activity in the C-Terminal Region of WRN()
Werner syndrome (WS) is a rare autosomal recessive disorder in humans characterized by premature aging and genetic instability. WS is caused by mutations in the WRN gene, which encodes a member of the RecQ family of DNA helicases. Cellular and biochemical studies suggest that WRN plays roles in DNA...
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| Udgivet i: | Biochemistry |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4586260/ https://ncbi.nlm.nih.gov/pubmed/18771289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800807n |
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