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Angiotensin II receptor blockade promotes repair of skeletal muscle through down-regulation of aging-promoting C1q expression
Disruption of angiotensin II type 1 (AT(1)) receptor prolonged life span in mice. Since aging-related decline in skeletal muscle function was retarded in Atgr1a(−/−) mice, we examined the role of AT(1) receptor in muscle regeneration after injury. Administration of AT(1) receptor blocker irbesartan...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4585890/ https://ncbi.nlm.nih.gov/pubmed/26571361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14453 |
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