Calpain-dependent Cleavage of N-cadherin Is Involved in the Progression of Post-myocardial Infarction Remodeling

Enzymatic proteolysis by calpains, Ca(2+)-dependent intracellular cysteine proteases, has been implicated in pathological processes such as cellular degeneration or death. Here, we investigated the role of calpain activation in the hearts subjected to myocardial infarction. We produced myocardial in...

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Hlavní autoři: Kudo-Sakamoto, Yoko, Akazawa, Hiroshi, Ito, Kaoru, Takano, Jiro, Yano, Masamichi, Yabumoto, Chizuru, Naito, Atsuhiko T., Oka, Toru, Lee, Jong-Kook, Sakata, Yasushi, Suzuki, Jun-ichi, Saido, Takaomi C., Komuro, Issei
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Molecular Bases of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094052/
https://ncbi.nlm.nih.gov/pubmed/24891510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.567206
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