Calpain-dependent Cleavage of N-cadherin Is Involved in the Progression of Post-myocardial Infarction Remodeling

Enzymatic proteolysis by calpains, Ca(2+)-dependent intracellular cysteine proteases, has been implicated in pathological processes such as cellular degeneration or death. Here, we investigated the role of calpain activation in the hearts subjected to myocardial infarction. We produced myocardial in...

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Dades bibliogràfiques
Autors principals: Kudo-Sakamoto, Yoko, Akazawa, Hiroshi, Ito, Kaoru, Takano, Jiro, Yano, Masamichi, Yabumoto, Chizuru, Naito, Atsuhiko T., Oka, Toru, Lee, Jong-Kook, Sakata, Yasushi, Suzuki, Jun-ichi, Saido, Takaomi C., Komuro, Issei
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
Matèries:
Molecular Bases of Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094052/
https://ncbi.nlm.nih.gov/pubmed/24891510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.567206
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