Calpain-dependent Cleavage of N-cadherin Is Involved in the Progression of Post-myocardial Infarction Remodeling

Enzymatic proteolysis by calpains, Ca(2+)-dependent intracellular cysteine proteases, has been implicated in pathological processes such as cellular degeneration or death. Here, we investigated the role of calpain activation in the hearts subjected to myocardial infarction. We produced myocardial in...

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Detalhes bibliográficos
Main Authors: Kudo-Sakamoto, Yoko, Akazawa, Hiroshi, Ito, Kaoru, Takano, Jiro, Yano, Masamichi, Yabumoto, Chizuru, Naito, Atsuhiko T., Oka, Toru, Lee, Jong-Kook, Sakata, Yasushi, Suzuki, Jun-ichi, Saido, Takaomi C., Komuro, Issei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094052/
https://ncbi.nlm.nih.gov/pubmed/24891510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.567206
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