Dual E627K and D701N mutations in the PB2 protein of A(H7N9) influenza virus increased its virulence in mammalian models

The ongoing avian H7N9 influenza outbreaks in China have caused significant human fatal cases and the virus is becoming established in poultry. Mutations with potential to increase mammalian adaptation have occurred in the polymerase basic protein 2 (PB2) and other viral genes. Here we found that du...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Zhu, Wenfei, Li, Long, Yan, Zhigang, Gan, Tanhuan, Li, Lifeng, Chen, Rirong, Chen, Ruidong, Zheng, Zuoyi, Hong, Wenshan, Wang, Jia, Smith, David K., Guan, Yi, Zhu, Huachen, Shu, Yuelong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2015
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585756/
https://ncbi.nlm.nih.gov/pubmed/26391278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14170
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items