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Substitution of D701N in the PB2 protein could enhance the viral replication and pathogenicity of Eurasian avian-like H1N1 swine influenza viruses

Eurasian avian-like H1N1 (EA H1N1) swine influenza viruses (SIVs) have become predominant in pig populations in China and have recently been reported to have the most potential to raise the next pandemic in humans. The mutation D701N in the PB2 protein, which accounts for 31% of H1N1 SIVs, has previ...

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書目詳細資料
發表在:Emerg Microbes Infect
Main Authors: Liu, Suli, Zhu, Wenfei, Feng, Zhaomin, Gao, Rongbao, Guo, Junfeng, Li, Xiyan, Liu, Jia, Wang, Dayan, Shu, Yuelong
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931605/
https://ncbi.nlm.nih.gov/pubmed/29717109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41426-018-0073-6
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