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TRPV4 channel activation selectively inhibits tumor endothelial cell proliferation

Endothelial cell proliferation is a critical event during angiogenesis, regulated by both soluble factors and mechanical forces. Although the proliferation of tumor cells is studied extensively, little is known about the proliferation of tumor endothelial cells (TEC) and its contribution to tumor an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Thoppil, Roslin J., Adapala, Ravi K., Cappelli, Holly C., Kondeti, Vinay, Dudley, Andrew C., Gary Meszaros, J., Paruchuri, Sailaja, Thodeti, Charles K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585691/
https://ncbi.nlm.nih.gov/pubmed/26388427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14257
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