Highly efficient CRISPR/Cas9-mediated transgene knockin at the H11 locus in pigs

Transgenic pigs play an important role in producing higher quality food in agriculture and improving human health when used as animal models for various human diseases in biomedicine. Production of transgenic pigs, however, is a lengthy and inefficient process that hinders research using pig models....

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Bibliographic Details
Published in:Sci Rep
Main Authors: Ruan, Jinxue, Li, Hegang, Xu, Kui, Wu, Tianwen, Wei, Jingliang, Zhou, Rong, Liu, Zhiguo, Mu, Yulian, Yang, Shulin, Ouyang, Hongsheng, Yanru Chen-Tsai, Ruby, Li, Kui
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585612/
https://ncbi.nlm.nih.gov/pubmed/26381350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14253
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