Differences in Signal Activation by LH and hCG are Mediated by the LH/CG Receptor’s Extracellular Hinge Region

The human lutropin (hLH)/choriogonadotropin (hCG) receptor (LHCGR) can be activated by binding two slightly different gonadotropic glycoprotein hormones, choriogonadotropin (CG) – secreted by the placenta, and lutropin (LH) – produced by the pituitary. They induce different signaling profiles at the...

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Detalhes bibliográficos
Publicado no:Front Endocrinol (Lausanne)
Main Authors: Grzesik, Paul, Kreuchwig, Annika, Rutz, Claudia, Furkert, Jens, Wiesner, Burkhard, Schuelein, Ralf, Kleinau, Gunnar, Gromoll, Joerg, Krause, Gerd
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585211/
https://ncbi.nlm.nih.gov/pubmed/26441830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2015.00140
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