Identification of Key Receptor Residues Discriminating Human Chorionic Gonadotropin (hCG)- and Luteinizing Hormone (LH)-Specific Signaling

(1) The human luteinizing hormone (LH)/chorionic gonadotropin (hCG) receptor (LHCGR) discriminates its two hormone ligands and differs from the murine receptor (Lhr) in amino acid residues potentially involved in qualitative discerning of LH and hCG. The latter gonadotropin is absent in rodents. The...

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Publicat a:Int J Mol Sci
Autors principals: Lazzaretti, Clara, Secco, Valentina, Paradiso, Elia, Sperduti, Samantha, Rutz, Claudia, Kreuchwig, Annika, Krause, Gerd, Simoni, Manuela, Casarini, Livio
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794846/
https://ncbi.nlm.nih.gov/pubmed/33375708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22010151
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