MicroRNA214 is Associated with Progression of Ulcerative Colitis, and Inhibition Reduces Development of Colitis and Colitis-associated Cancer in Mice

BACKGROUND & AIMS: Persistent activation of the inflammatory response contributes to development of inflammatory bowel diseases, which increase the risk of colorectal cancer. We aimed to identify microRNAs that regulate inflammation during development of ulcerative colitis (UC) and progression t...

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Vydáno v:Gastroenterology
Hlavní autoři: Polytarchou, Christos, Hommes, Daniel W., Palumbo, Tiziana, Hatziapostolou, Maria, Koutsioumpa, Marina, Koukos, Georgios, van der Meulen-de Jong, Andrea E., Oikonomopoulos, Angelos, van Deen, Welmoed K., Vorvis, Christina, Serebrennikova, Oksana B., Birli, Eleni, Choi, Jennifer, Chang, Lin, Anton, Peter A., Tsichlis, Philip N., Pothoulakis, Charalabos, Verspaget, Hein W., Iliopoulos, Dimitrios
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4584179/
https://ncbi.nlm.nih.gov/pubmed/26055138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2015.05.057
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