MicroRNA214 is Associated with Progression of Ulcerative Colitis, and Inhibition Reduces Development of Colitis and Colitis-associated Cancer in Mice

BACKGROUND & AIMS: Persistent activation of the inflammatory response contributes to development of inflammatory bowel diseases, which increase the risk of colorectal cancer. We aimed to identify microRNAs that regulate inflammation during development of ulcerative colitis (UC) and progression t...

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Publicado no:Gastroenterology
Principais autores: Polytarchou, Christos, Hommes, Daniel W., Palumbo, Tiziana, Hatziapostolou, Maria, Koutsioumpa, Marina, Koukos, Georgios, van der Meulen-de Jong, Andrea E., Oikonomopoulos, Angelos, van Deen, Welmoed K., Vorvis, Christina, Serebrennikova, Oksana B., Birli, Eleni, Choi, Jennifer, Chang, Lin, Anton, Peter A., Tsichlis, Philip N., Pothoulakis, Charalabos, Verspaget, Hein W., Iliopoulos, Dimitrios
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4584179/
https://ncbi.nlm.nih.gov/pubmed/26055138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2015.05.057
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