MicroRNA214 is Associated with Progression of Ulcerative Colitis, and Inhibition Reduces Development of Colitis and Colitis-associated Cancer in Mice

BACKGROUND & AIMS: Persistent activation of the inflammatory response contributes to development of inflammatory bowel diseases, which increase the risk of colorectal cancer. We aimed to identify microRNAs that regulate inflammation during development of ulcerative colitis (UC) and progression t...

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Publié dans:Gastroenterology
Auteurs principaux: Polytarchou, Christos, Hommes, Daniel W., Palumbo, Tiziana, Hatziapostolou, Maria, Koutsioumpa, Marina, Koukos, Georgios, van der Meulen-de Jong, Andrea E., Oikonomopoulos, Angelos, van Deen, Welmoed K., Vorvis, Christina, Serebrennikova, Oksana B., Birli, Eleni, Choi, Jennifer, Chang, Lin, Anton, Peter A., Tsichlis, Philip N., Pothoulakis, Charalabos, Verspaget, Hein W., Iliopoulos, Dimitrios
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4584179/
https://ncbi.nlm.nih.gov/pubmed/26055138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2015.05.057
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