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Impact of kinetic isotope effects in isotopic studies of metabolic systems

BACKGROUND: Isotope labeling experiments (ILEs) are increasingly used to investigate the functioning of metabolic systems. Some enzymes are subject to kinetic isotope effects (KIEs) which modulate reaction rates depending on the isotopic composition of their substrate(s). KIEs may therefore affect b...

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Publicat a:BMC Syst Biol
Autors principals: Millard, Pierre, Portais, Jean-Charles, Mendes, Pedro
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583766/
https://ncbi.nlm.nih.gov/pubmed/26410690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-015-0213-8
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