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Impact of kinetic isotope effects in isotopic studies of metabolic systems

BACKGROUND: Isotope labeling experiments (ILEs) are increasingly used to investigate the functioning of metabolic systems. Some enzymes are subject to kinetic isotope effects (KIEs) which modulate reaction rates depending on the isotopic composition of their substrate(s). KIEs may therefore affect b...

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Detalhes bibliográficos
Publicado no:BMC Syst Biol
Main Authors: Millard, Pierre, Portais, Jean-Charles, Mendes, Pedro
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583766/
https://ncbi.nlm.nih.gov/pubmed/26410690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-015-0213-8
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