Polymorphisms in Genes of Relevance for Oestrogen and Oxytocin Pathways and Risk of Barrett’s Oesophagus and Oesophageal Adenocarcinoma: A Pooled Analysis from the BEACON Consortium

BACKGROUND: The strong male predominance in oesophageal adenocarcinoma (OAC) and Barrett’s oesophagus (BO) continues to puzzle. Hormonal influence, e.g. oestrogen or oxytocin, might contribute. METHODS: This genetic-epidemiological study pooled 14 studies from three continents, Australia, Europe, an...

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Publicat a:PLoS One
Autors principals: Lagergren, Katarina, Ek, Weronica E., Levine, David, Chow, Wong-Ho, Bernstein, Leslie, Casson, Alan G., Risch, Harvey A., Shaheen, Nicholas J., Bird, Nigel C., Reid, Brian J., Corley, Douglas A., Hardie, Laura J., Wu, Anna H., Fitzgerald, Rebecca C., Pharoah, Paul, Caldas, Carlos, Romero, Yvonne, Vaughan, Thomas L., MacGregor, Stuart, Whiteman, David, Westberg, Lars, Nyren, Olof, Lagergren, Jesper
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583498/
https://ncbi.nlm.nih.gov/pubmed/26406593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138738
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