Polymorphisms in Genes of Relevance for Oestrogen and Oxytocin Pathways and Risk of Barrett’s Oesophagus and Oesophageal Adenocarcinoma: A Pooled Analysis from the BEACON Consortium

BACKGROUND: The strong male predominance in oesophageal adenocarcinoma (OAC) and Barrett’s oesophagus (BO) continues to puzzle. Hormonal influence, e.g. oestrogen or oxytocin, might contribute. METHODS: This genetic-epidemiological study pooled 14 studies from three continents, Australia, Europe, an...

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Vydáno v:PLoS One
Hlavní autoři: Lagergren, Katarina, Ek, Weronica E., Levine, David, Chow, Wong-Ho, Bernstein, Leslie, Casson, Alan G., Risch, Harvey A., Shaheen, Nicholas J., Bird, Nigel C., Reid, Brian J., Corley, Douglas A., Hardie, Laura J., Wu, Anna H., Fitzgerald, Rebecca C., Pharoah, Paul, Caldas, Carlos, Romero, Yvonne, Vaughan, Thomas L., MacGregor, Stuart, Whiteman, David, Westberg, Lars, Nyren, Olof, Lagergren, Jesper
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583498/
https://ncbi.nlm.nih.gov/pubmed/26406593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138738
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