Polymorphisms in genes in the androgen pathway and risk of Barrett’s esophagus and esophageal adenocarcinoma

The strong male predominance in Barrett’s esophagus (BE) and esophageal adenocarcinoma (EAC) remains inadequately explained, but sex hormones might be involved. We hypothesized that single nucleotide polymorphisms (SNPs) in the androgen pathway influence risk of developing BE and EAC. This genetic-e...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Ek, Weronica E., Lagergren, Katarina, Cook, Michael, Wu, Anna H., Abnet, Christian C., Levine, David, Chow, Wong-Ho, Bernstein, Leslie, Risch, Harvey A., Shaheen, Nicholas J., Bird, Nigel C., Corley, Douglas A., Hardie, Laura J., Fitzgerald, Rebecca C., Gammon, Marilie D., Romero, Yvonne, Liu, Geoffrey, Ye, Weimin, Vaughan, Thomas L., MacGregor, Stuart, Whiteman, David C., Westberg, Lars, Lagergren, Jesper
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715576/
https://ncbi.nlm.nih.gov/pubmed/26414697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29863
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