Polymorphisms in genes in the androgen pathway and risk of Barrett’s esophagus and esophageal adenocarcinoma

The strong male predominance in Barrett’s esophagus (BE) and esophageal adenocarcinoma (EAC) remains inadequately explained, but sex hormones might be involved. We hypothesized that single nucleotide polymorphisms (SNPs) in the androgen pathway influence risk of developing BE and EAC. This genetic-e...

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Veröffentlicht in:Int J Cancer
Hauptverfasser: Ek, Weronica E., Lagergren, Katarina, Cook, Michael, Wu, Anna H., Abnet, Christian C., Levine, David, Chow, Wong-Ho, Bernstein, Leslie, Risch, Harvey A., Shaheen, Nicholas J., Bird, Nigel C., Corley, Douglas A., Hardie, Laura J., Fitzgerald, Rebecca C., Gammon, Marilie D., Romero, Yvonne, Liu, Geoffrey, Ye, Weimin, Vaughan, Thomas L., MacGregor, Stuart, Whiteman, David C., Westberg, Lars, Lagergren, Jesper
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715576/
https://ncbi.nlm.nih.gov/pubmed/26414697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29863
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